美国梅奥诊所博士后职位—肺干细胞生物学

美国梅奥诊所博士后职位—肺干细胞生物学

梅奥医疗集团又称梅奥诊所，梅约诊所，马约诊所，梅奥医疗集团或梅奥医疗中心，是世界著名的私立非营利性医疗机构。梅奥于1864年在美国明尼苏达州罗切斯特市创建。美国梅奥虽被称为“诊所”，但实际上是一所拥有悠久历史的综合医疗集团公司。

POSTDOCTORAL POSITION IN LUNG STEM CELL BIOLOGY

Employer

De Langhe lab at Mayo Clinic Rochester

Location

Mayo Clinic Rochester, Minnesota (US)

Salary

61,000-74,000

Closing date

Aug 13, 2024

The De Langhe Laboratory at Mayo Clinic Rochester studies lung development, repair and regeneration in order to improve pulmonary disease such as lung fibrosis, influenza and covid induced ARDS or COPD. We utilize single cell transcriptomics, genetically engineered mouse models and 3D organotypic cultures to characterize cellular/microenvironmental processes that underly lung tissue construction, deconstruction and reconstruction, identify molecular mechanisms governing cell fate selection and cell plasticity, and develop regenerative therapies.

https://www.ncbi.nlm.nih.gov/myncbi/stijn.de%20langhe.1/bibliography/public/?sortby=pubDate&sdirection=descending

This Postdoctoral Scientist position is available at the laboratory of Dr. De Langhe at Mayo Clinic Rochester to investigate mechanisms of lung regeneration. Experimental approaches employed in our lab involve molecular biology, genetically modified mice, lineage tracing, lung injury models, prospective isolation and organoid culture of lung stem cells, single cell RNA-seq and genomics/epigenetics studies.

As a Postdoctoral Scientist, you will be working independently but in close cooperation and in consultation with the Principal Investigator and other Research scientists and will perform routine and complex laboratory procedures throughout the training period. In this role, you may develop, adapt, and implement new research techniques and protocols.

Primary Duties and Responsibilities:

May assist in preparation of grant proposals. May participate in publications and presentations as author or co-author. Designs and performs experiments. Will keep appropriate experimental records and documentation, and analyze the results. Analyzes, interprets, summarizes, and compiles data. Operates and maintains equipment and instruments.

Education:

Doctorate (PhD) in area directly related to field of research specialization. A recent PhD or MD/PhD in developmental biology, bioinformatics or molecular biology is preferred.

Experience:

Works independently on research projects designed by a mentor (typically the PI) within area of specialization. Hands-on experience with mouse work, transgenic/knockout mouse models, advanced fluorescence and confocal imaging, biochemistry, molecular biology, cell culture, flow cytometry, gene expression, ChIP, quantitative analysis, single cell RNAseq/ATACseq/bioinformatics analysis. Strong publication record in peer-reviewed journals is required. Acquires complete technical and theoretical knowledge of research project and objectives during one to five (1-5) year post-doctoral appointment.

Physical Demands:

Able to perform moderate lifting. Able to sit, stand and walk for prolonged periods of time. Able to read papers and online documents in English. Able to operate standard office equipment. Able to exercise physical ability and perspective acuity to satisfactorily perform essential job functions.

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