瑞典斯德哥尔摩大学单细胞microRNA功能的研究博士后职位招聘

　　瑞典斯德哥尔摩大学单细胞microRNA功能的研究博士后职位招聘

　　Two postdoctoral researchers to study microRNA functions in single  cells

　　·         SciLifeLab / Stockholm University

　　·         Location: Stockholm, Sweden

　　·         Job Number: 7061740

　　·         Posting Date: Oct 25, 2019

　　·         Application Deadline: Nov 16, 2019

　　Job Description

　　Two postdoctoral researchers to study microRNA functions in single  cells

　　Stockholm University and SciLifeLab, Sweden

　　Stockholm, Sweden

　　Institutions

　　Science for Life Laboratory (SciLifeLab) is a collaboration between four  universities in Stockholm and Uppsala: Stockholm University, the Karolinska  Institute, the Royal Institute of Technology, and Uppsala University. The  SciLifeLab is a national center for large-scale biosciences with a focus on  high-throughput health and environmental research. The center combines advanced  technical know-how and cutting-edge equipment with a broad knowledge in  translational medicine and molecular biosciences. In particular, SciLifeLab has  in the recent years become an international hub for research in single-cell and  spatial transcriptomics.

　　Stockholm University is a leading European university offering a  multicultural environment in one of the world’s most dynamic capital cities.  With more than 60,000 students and 5,000 staff, the University facilitates  individual and societal development by providing top quality education that is  tightly linked to its internationally recognized research programs. The MBW  department conducts experimental basic research in molecular cell biology,  integrative biology and infection and immune biology.

　　Research project

　　The postdoctoral positions are available in the Quantitative RNA Biology  group headed by associate professor Marc Friedlander, part of MBW and located at  the SciLifeLab. The group is part of a larger vibrant international  collaborative environment and seeks to address fundamental questions in RNA  biology, by applying quantitative approaches such as single-cell RNA sequencing,  single-cell proteomics, various high-throughput screening methods and advanced  computational biology.

　　Recent collaborations include paleotranscriptomic profiling of mammoth  non-coding RNAs and study of the impact of space flight on the human  transcriptome (NASA Twin study). The main focus of the group is to study  microRNA functions in mammalian single cells, investigating the impact of  microRNAs on target gene expression variation, covariation and on overall gene  expression networks. This research direction is funded by an ERC Starting Grant  (miRCell 758397).

　　The postdoctoral researchers will develop beyond-state-of-the-art methods  to profile the variation of microRNA expression, interactions between microRNAs  and their targets, and the impact of microRNAs on the transcriptome and  proteome, in single cells. The post docs will interact with experimental and  computational researchers from the group, and will participate in limited  co-supervision of PhD students.

　　Lab website: www.friedlanderlab.org

　　Twitter: www.twitter/friedlanderlab

　　Recent pre-print on gene covariance:  www.biorxiv.org/content/10.1101/771402v1

　　Recent pre-print on single-cell proteomics:  www.biorxiv.org/content/10.1101/749473v3

　　Eligibility

　　Postdoctoral positions are appointed primarily for purposes of research.  Applicants are expected to hold a Swedish doctoral degree or an equivalent  degree from another country.

　　Selection criteria

　　In the appointment process, special attention will be given to research  skills. We are looking for candidates that have extensive wet-lab experience  with transcriptomic or proteomic methods, preferably in a single-cell context.  Specific experience with single-molecule FISH, microfluidics, oligo-assisted  proteomics, PEA or PLA constitutes an additional advantage. Familiarity with the  microRNA field is not necessary, however the candidates must be highly  motivated, creatively thinking and have a record of high-quality scientific  publications. Excellent English language skills, both written and spoken, are a  requisite.

　　Terms of Employment

　　This is a full-time position available immediately. The starting date is  negotiable. The position is initially funded for two years, with a possibility  of extension. The position constitutes full employment including all social  benefits. Stockholm University strives to be a workplace free from  discrimination and with equal opportunities for all.

　　Contact

　　Further information can be provided by associate professor Marc  Friedlander, marc.friedlander@scilifelab.se

　　Application

　　Applications should be submitted until the 16th of November using the  Stockholm University web-based application system at:  www.su.se/english/about/working-at-su/jobs?rmpage=job&rmjob=10155&rmlang=UK

　　The instructions for applicants are available at:  www.su.se/english/about/working-at-su/instructions-applicants

　　You are welcome to apply!

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