英国剑桥大学生理学、发育与神经科学系博士后

2023年01月10日

来源：知识人网整理

摘要：

英国剑桥大学生理学、发育与神经科学系博士后

剑桥大学（University of Cambridge；勋衔：Cantab），坐落于英国剑桥郡，是一所公立研究型大学，采用传统学院制。学校是罗素大学集团成员，全球大学校长论坛成员，被誉为“金三角名校”和“G5”之一。剑桥大学是英语世界中第二古老的大学，前身是一个于1209年成立的学者协会。

Postdoctoral Research Associate to study the role of dopamine in hippocampal plasticity and spatial memory (Fixed Term)

University of Cambridge

Postdoctoral Research Associate to study the role of dopamine in hippocampal plasticity and spatial memory (Fixed Term)

Applications are invited for a postdoctoral research associate position to study the role of dopamine in mouse hippocampal plasticity and spatial memory. The project will be based in the laboratory of Professor Ole Paulsen in the Department of Physiology, Development and Neuroscience at the University of Cambridge.

The successful candidate will investigate (1) the effect of optogenetically released dopamine on previously primed synapses in mouse hippocampal slices, and (2) the role of dopamine released in the hippocampus from either the ventral tegmental area (VTA) or locus coeruleus (LC) in reward-based spatial memory in freely moving mice. The project will combine optogenetics and electrophysiology both in vivo and ex vivo.

Applicants should have completed (or be about to submit) a PhD in neuroscience, biology, experimental psychology, engineering, or other relevant disciplines. We are looking for someone with previous experience in electrophysiology/optogenetics and/or behavioural training in mice, and strong data analysis skills (e.g. Matlab, R, or Python).

The research position is available from 1 April 2023 for up to 3 years. For more information about the lab see https: // noggin.pdn.cam.ac.uk/.

Informal enquiries about the position can be made to Ole Paulsen (op210@cam.ac.uk).

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

To apply for this post, please submit a CV and covering letter, as well as the contact details of two referees. In addition, applicants are requested to provide a brief statement (~500 words) describing the questions and approach they consider important for the study of hippocampal learning and memory and their future career ambitions.

Closing date: 31 January 2023.

Interviews are expected to be held in mid February 2023.

Please quote reference PM34843 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society. The Department of Physiology, Development & Neuroscience particularly encourages women and candidates from a Black, Asian or Minority Ethnic background to apply for this vacancy.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Background: 1) Brzosko Z, Mierau S, Paulsen O (2019) Neuromodulation of spike timing-dependent plasticity: Past, present, and future. Neuron 103 : 563-581.

2) Fuchsberger T, Jarzebowski P, Clopath C, Brzosko Z, Wang H, Paulsen O (2022) Reactivation of hippocampal neurons enables associative plasticity of temporally discontiguous inputs. eLife 11 : e81071. DOI: https: // doi.org/10.7554/eLife.81071.

3) Jarzebowski P, Hay YA, Grewe BF, Paulsen O (2022) Different encoding of reward location in dorsal and intermediate hippocampus. CurrBiol 32 : 834-841. DOI: https: // doi.org/10.1016/j.cub.2021.12.024.

Further information

Further Particulars

Department/Location

Department of Physiology, Development and Neuroscience

Salary

£34,308-£42,155

Reference

PM34843